Call me Back
Dr. Mahjabeen Saleem

Dr. Mahjabeen Saleem
( Professor )

Contact Details

• The research included the identification of protein and DNA biomarkers in cancer and other disease screening and their use in therapeutic discoveries. Cancer serum protein profiling coupled with immunological confirmation serve as candidates for cancer biomarkers, finding new therapeutic targets and improving the survival rates of cancer patients. • To study association of genetic polymorphisms with a variety of medical diseases, their genetic basis and to assess disease risks. • The scholarly activity focuses on applications of industrially important enzymes. Since environmental pollution has led the industries to reform new systems for the reduction of various pollutants and make the environment friendly. Uses of such enzymes allow the development of products and processes which are more sustainable and environment friendly. • The research focuses on the characterization of industrially important thermally stable microbial enzymes proteases such as hemicellulases, cellulases, proteases, pectinases, chitinases. Their overproduction and improvement through genetic manipulation by cloning and expression in E. coli under the control of suitable promoters. Applications of these enzymes in food, textile, paper and pulp industries. • The research is focused on the investigative and therapeutic studies for viral & bacterial infectious diseases. Bioinformatics/AI tools are playing essential role in these therapies by developing vaccines and designing and finding drugs against these infections. Such methods contribute to save massive time and their chemical cost as well. • Environmental pollution has led the different industries to sort out new techniques for the reduction of various pollutants in the effluents emitting from the bleaching plants of industries. The study included the characterization of thermophilic and extreme thermophilic bacterial species and their importance in bioremediation of various industrial wastes.

  • Ph.D, University of the Punjab (1999)

Title Volume.# Issue.# Pages Year
TULP3 NLS inhibition: an in silico study to hamper cargo transport to nucleus
Journal Name: Journal of Biomolecular Structure and Dynamics
Volume # 5 Page # 1-9 Year of Publication: 2022
A computer aided drug discovery based discovery of lead-like compounds against KDM5A for cancers using pharmacophore modeling and high-throughput virtual screening
Journal Name: Proteins
Volume # 90 Issue # 3 Page # 645-657 Year of Publication: 2022
Development of multi-epitope vaccine constructs for non-small cell lung cancer (NSCLC) against USA human leukocyte antigen background: an immunoinformatic approach toward future vaccine designing
Journal Name: Expert Opinion on Biological Therapy
Volume # 21 Issue # 11 Page # 1525-1533 Year of Publication: 2021
A Computational Approach to Modeling an Antagonistic Angiogenic VEGFR1-IL2 Fusion Protein for Cancer Therapy
Journal Name: Bioinformatics and Biology Insights
Volume # 20 Page # 15 Year of Publication: 2021
A Putative Prophylactic Solution for COVID‐19: Development of Novel Multiepitope Vaccine Candidate against SARS‐COV‐2 by Comprehensive Immunoinformatic and Molecular Modelling Approach.
Journal Name: Biology
Volume # 9 Page # 226 Year of Publication: 2020
Molecular cloning and characterization of an acidic polygalacturonase from grapes and its potential in industry.
Journal Name: Critical Reviews™ in Eukaryotic Gene Expression
Volume # 30 Issue # 5 Page # 411–425 Year of Publication: 2020
Analysis of remediation potential of whole bacterial cells on wastewater decolourisation and detoxification
Journal Name: Biocatalysis and Agricultural Biotechnology,
Volume # 24 Page # 101557 Year of Publication: 2020
Paromomycin: A potential dual targeted drug effectively inhibits both spike (S1) and main protease of COVID-19
Journal Name: International Journal of Infectious Diseases
Volume # 98 Page # 116-175 Year of Publication: 2020
Characterization of recombinant endo-1,4-β-xylanase of Bacillus halodurans C-125 and rational identification of hot spot amino acid residues responsible for enhancing thermostability by an in-silico approach.
Journal Name: Molecular Biology Reports
Volume # 46 Issue # 4 Year of Publication: 2019
Bacterial expression and characterization of recombinant β-xylosidase from the thermophilic xylanolytic bacterium Bacillus sp.
Journal Name: Critical Reviews™ in Eukaryotic Gene Expression.
Volume # 29 Issue # 4 Page # 305-317 Year of Publication: 2019
Mutagenesis of DsbAss is crucial for the signal recognition particle mechanism in Escherichia coli: Insights from Molecular Dynamics Simulations.
Journal Name: Biomolecules
Volume # 9 Page # 133 Year of Publication: 2019
Soluble production of human recombinant VEGF-A121 by using SUMO fusion technology in Escherichia coli
Journal Name: Molecular Biotechnology
Volume # 60 Issue # 8 Page # 585-594 Year of Publication: 2018
Molecular characterization, structural modeling, and evaluation of antimicrobial activity of Basrai Thaumatin-like protein against fungal infection
Journal Name: BioMed Research International
Volume # 1 Issue # 9 Page # 504645 Year of Publication: 2017
Seroprevalence of asymptomatic dengue infection in children in Lahore
Journal Name: Epidemiology and Infection
Volume # 144 Issue # 11 Page # 2276-2282 Year of Publication: 2016
Glycosylated alpha-1-acid glycoprotein 1 as a potential lung cancerserum biomarker
Journal Name: International Journal of Biochemistry & Cell Biology
Volume # 70 Page # 68–75 Year of Publication: 2016
Mass spectrometric identification, characterization and validation of haptoglobin beta chain protein as lung cancer serum biomarker
Journal Name: Molecular Medicine Reports
Volume # 12 Page # 3755-3762 Year of Publication: 2015
Association of FcγRIIa polymorphism with clinical outcome of dengue Infection: First insight from Pakistan
Journal Name: The American Journal of Tropical Medicine and Hygiene
Volume # 93 Issue # 4 Page # 691-696 Year of Publication: 2015
Potential of Bacillus cereus for bioremediation of pulp and paper industry wastes
Journal Name: Annals of Microbiology
Volume # 64 Page # 823–829 Year of Publication: 2014
Biochemical characterization of fruit-specific pathogenesis-related antifungal protein from basari banana
Journal Name: Microbiological Research
Volume # 169 Issue # 5–6 Page # 369–377 Year of Publication: 2014
Biochemical analysis and investigation on the prospective applications of alkaline protease from a Bacillus cereus strain
Journal Name: Molecular Biology Reports
Volume # 39 Issue # 6 Page # 6399-6408 Year of Publication: 2012
Characterization of a thermostable and alkaline xylanase from Bacillus sp. and its bleaching impact on wheat straw pulp
Journal Name: World Journal of Microbiologyand Biotechnology
Volume # 28 Issue # 2 Page # 513-522